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Creators/Authors contains: "Walczak, Maciej A"

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  1. ; ; ; (, Organic Letters)
    Free, publicly-accessible full text available June 18, 2026
  2. ; ; ; ; (, Journal of the American Chemical Society)
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  3. ; (, Organic Letters)
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  4. ; ; ; (, Chem Catalysis)
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  5. ; (, Journal of the American Chemical Society)
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  6. ; ; (, The Journal of Organic Chemistry)
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  7. ; (, The Journal of Organic Chemistry)
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  8. ; ; ; ; ; (, Journal of the American Chemical Society)
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  9. ; ; ; (, Chemical Science)
    Thiopeptides are a class of potent antibiotics with promising therapeutic potential. We developed a novel Mo( vi )-oxide/picolinic acid catalyst for the cyclodehydration of cysteine peptides to form thiazoline heterocycles. With this powerful tool in hand, we completed the total syntheses of two representative thiopeptide antibiotics: micrococcin P1 and thiocillin I. These two concise syntheses (15 steps, longest linear sequence) feature a C–H activation strategy to install the trisubstituted pyridine core and thiazole groups. The synthetic material displays promising antimicrobial properties measured against a series of Gram-positive bacteria. 
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  10. ; ; (, Organic Letters)
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